As Kenya puts more HIV-positive children on life-prolonging antiretroviral (ARV) drugs, experts are warning that unless more effort is put into ensuring the medicines are taken regularly, widespread treatment failure could result. 'It is very hard to maintain adherence in children because they rely on others to give them medicine, some change regimens as they grow into adolescence and they can hardly cope with the many drugs they are expected to take,' said Dr Andrew Suleh, medical superintendent at the Mbagathi District Hospital in the capital, Nairobi.