"We all know that the stigma and discrimination associated with AIDS continue to fuel its spread and exacerbate its impact. Developing countries, where AIDS and poverty are now mutually reinforcing negative forces, continue to bear the overwhelming burden of the epidemic. In sub-Saharan Africa AIDS is the leading cause of death. AIDS has left in its wake millions of orphans at risk of hunger, neglect and exploitation – and this number is set to rise to the tens of millions in the space of a few years if the spread of the epidemic is not curtailed."