This report, published by the World Health Organisation, outlines progress made by the Stop TB Partnership in meeting the objectives of the Global Plan to Stop Tuberculosis (GPSTB). Achievements highlighted include the implementation of DOTs in 180 countries and the establishment of pilot projects for joint HIV/TB control and for treatment of patients with multi-drug resistant TB (MDR-TB). Recommendations include more streamlined evaluation of new drugs and diagnostic tools, and targeted distribution of approved vaccines to areas where the TB burden is greatest. In conclusion, the report calls for urgent large-scale investment of both financial and human resources to accelerate progress and ensure the 2005 TB reduction targets are met.