This report argues that Sub-Saharan African (SSA) countries that have not sufficiently addressed the acquisition of scientific and technological knowledge must redouble their efforts with a strategy that begins with the popularisation of science and its application to development. It also argues that the key issue should be the empowerment of individuals and groups, to be able to use scientific knowledge and technological know-how to address problems like prevention and treatment of HIV/AIDS and other public health crises, food security and nutrition, high unemployment, drought, and water supply.